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1

Trends in Glycosylation, Glycoanalysis and Glycoengineering of Therapeutic Antibodies and Fc-Fusion Proteins

Beck, Alain, Wagner-Rousset, Elsa, Bussat, Marie-Claire, Lokteff, Maryline, Klinguer-Hamour, Christine, Haeuw, Jean-François, Goetsch, Liliane, Wurch, Thierry, Dorsselaer, Alain, Corvaia, Nathalie

Journal:

Current Pharmaceutical Biotechnology

Year:

2008

Language:

english

File:

PDF, 989 KB

english, 2008

2

Identification and characterisation of multiple linear B cell protectopes in the respiratory syncytial virus G protein

Ultan F. Power, Hélène Plotnicky-Gilquin, Liliane Goetsch, Thierry Champion, Alain Beck, Jean-François Haeuw, Thien Ngoc Nguyen, Jean-Yves Bonnefoy, Nathalie Corvaı̈a

Journal:

Year:

2001

Language:

english

File:

PDF, 132 KB

english, 2001

3

Tetraspanin CD151 as a target for antibody-based cancer immunotherapy

Haeuw, Jean‑François, Goetsch, Liliane, Bailly, Christian, Corvaia, Nathalie

Journal:

Biochemical Society Transactions

Year:

2011

Language:

english

File:

PDF, 408 KB

english, 2011

4

Endotoxin-free heat-shock protein 70 fails to induce APC activation

Huguette Bausinger, Dan Lipsker, Umit Ziylan, Serge Manié, Jean-Paul Briand, Jean-Pierre Cazenave, Sylviane Muller, Jean-François Haeuw, Catherine Ravanat, Henri de la Salle, Daniel Hanau

Journal:

European Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 145 KB

english, 2002

5

A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts

Liliane Goetsch, Alexandra Gonzalez, Olivier Leger, Alain Beck, Petrus J. Pauwels, Jean François Haeuw, Nathalie Corvaia

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 959 KB

english, 2005

6

Characterization by liquid chromatography combined with mass spectrometry of monoclonal anti-IGF-1 receptor antibodies produced in CHO and NS0 cells

Alain Beck, Marie-Claire Bussat, Nathalie Zorn, Virginie Robillard, Christine Klinguer-Hamour, Stéphane Chenu, Liliane Goetsch, Nathalie Corvaïa, Alain Van Dorsselaer, Jean-François Haeuw

Journal:

Journal of Chromatography B

Year:

2005

Language:

english

File:

PDF, 603 KB

english, 2005

7

Separation and quantitative analysis of alkyl sulfobetaine-type detergents by high-performance liquid chromatography and light-scattering detection

Laurence Zanna, Jean-François Haeuw

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 257 KB

english, 2007

8

Synthesis and characterization of Respiratory Syncytial Virus protein G related peptides containing two disulfide bridges

A. Beck, M.C. Bussat, J.F. Haeuw, N. Corvaïa, T.N. Nguyen, J.Y. Bonnefoy, N. Zorn, A. Van Doersselaer

Journal:

Chemical Biology & Drug Design

Year:

2000

Language:

english

File:

PDF, 310 KB

english, 2000

9

Stability and CTL activity of N-terminal glutamic acid containing peptides

A. Beck, M.-C. Bussat, C. Klinguer-Hamour, L. Goetsch, J.-P. Aubry, T. Champion, E. Julien, J.-F. Haeuw, J.-Y. Bonnefoy, N. Corvaia

Journal:

Chemical Biology & Drug Design

Year:

2001

Language:

english

File:

PDF, 240 KB

english, 2001

10

Structure−antigenicity relationship studies of the central conserved region of human respiratory syncytial virus protein G

M. Sugawara, J. Czaplicki, J. Ferrage, A. Milon, J.-F. Haeuw, U. F. Power, N. Corvaïa, T. Nguyen, A. Beck

Journal:

Chemical Biology & Drug Design

Year:

2002

Language:

english

File:

PDF, 260 KB

english, 2002

11

Glycoproteomics and glycomics investigation of membrane N-glycosylproteins from human colon carcinoma cells

Anne-Sophie Vercoutter-Edouart, Marie-Christine Slomianny, Olivia Dekeyzer-Beseme, Jean-François Haeuw, Jean-Claude Michalski

Journal:

Year:

2008

Language:

english

File:

PDF, 642 KB

english, 2008

12

Peptides as tools and drugs for immunotherapies

Alain Beck, Christine Klinguer-Hamour, Marie-Claire Bussat, Thierry Champion, Jean-François Haeuw, Liliane Goetsch, Thierry Wurch, Masae Sugawara, Alain Milon, Alain Van Dorsselaer, Thien Nguyen, Nath

Journal:

Journal of Peptide Science

Year:

2007

Language:

english

File:

PDF, 1.78 MB

english, 2007

13

Stability and CTL-activity of P40/ELA Melanoma Vaccine Candidate

A. Beck, L. Goetsch, T. Champion, M.-C. Bussat, J.-P. Aubry, C. Klinguer-Hamour, J.-F. Haeuw, J.-Y. Bonnefoy, N. Corvaı̈a

Journal:

Year:

2001

Language:

english

File:

PDF, 1.02 MB

english, 2001

14

Absence of Lung Immunopathology Following Respiratory Syncytial Virus (RSV) Challenge in Mice Immunized with a Recombinant RSV G Protein Fragment

Hélène Plotnicky-Gilquin, Thierry Huss, Jean-Pierre Aubry, Jean-François Haeuw, Alain Beck, Jean-Yves Bonnefoy, Thien Ngoc Nguyen, Ultan F. Power

Journal:

Year:

1999

Language:

english

File:

PDF, 220 KB

english, 1999

15

Development of a quantitative assay for residual host cell proteins in a recombinant subunit vaccine against human respiratory syncytial virus

Nathalie Dagouassat, Jean-François Haeuw, Virginie Robillard, Fabienne Damien, Christine Libon, Nathalie Corvaı̈a, François Lawny, Thien Ngoc Nguyen, Jean-Yves Bonnefoy, Alain Beck

Journal:

Journal of Immunological Methods

Year:

2001

Language:

english

File:

PDF, 326 KB

english, 2001

16

The recombinant Klebsiella pneumoniae outer membrane protein OmpA has carrier properties for conjugated antigenic peptides

Jean-François Haeuw, Isabelle Rauly, Laurence Zanna, Christine Libon, Christine Andreoni, Thien Ngoc Nguyen, Thierry Baussant, Jean-Yves Bonnefoy, Alain Beck

Journal:

Year:

1998

Language:

english

File:

PDF, 307 KB

english, 1998

17

In vitro hydrolysis of oligomannosyl oligosaccharides by the lysosomal α-d-mannosidases

Jean-Claude MICHALSKI, Jean-François HAEUW, Jean-Michel WIERUSZESKI, Jean MONTREUIL, Gérard STRECKER

Journal:

Year:

1990

Language:

english

File:

PDF, 765 KB

english, 1990

18

Substrate specificity of rat liver cytosolic α-d-mannosidase Novel degradative pathway for oligomannosidic type glycans

Jean-Françis HAEUW, Gerard STRECKER, Jean-Michel WIERUSZESKI, Jean MONTREUIL, Jean-Claude MICHALSKI

Journal:

Year:

1991

Language:

english

File:

PDF, 798 KB

english, 1991

19

Primary structure of human milk octa-, dodeca- and tridecasaccharides determined by a combination of 1H-NMR spectroscopy and fast-atom-bombardment mass spectrometry : Evidence for a new core structure, the para-lacto-N-octaose

Sophie HAEUW-FIEVRE, Jean-Michel WIERUSZESKI, Yves PLANCKE, Jean-Claude MICHALSKI, Jean MONTREUIL, Gérard STRECKER

Journal:

Year:

1993

Language:

english

File:

PDF, 730 KB

english, 1993

20

Soluble forms of α-d-mannosidases from rat liver : Separation and characterization of two enzymic forms with different substrate specificities

Thierry GRARD, Agnès SAINT-POL, Jean-François HAEUW, Catherine ALONSO, Jean-Michel WIERUSZESKI, Gérard STRECKER, Jean-Claude MICHALSKI

Journal:

Year:

1994

Language:

english

File:

PDF, 773 KB

english, 1994

21

Complexity and Complementarity of Outer Membrane Protein A Recognition by Cellular and Humoral Innate Immunity Receptors

Pascale Jeannin, Barbara Bottazzi, Marina Sironi, Andrea Doni, Marco Rusnati, Marco Presta, Virginia Maina, Giovanni Magistrelli, Jean François Haeuw, Guillaume Hoeffel, Nathalie Thieblemont, Nathalie

Journal:

Year:

2005

Language:

english

File:

PDF, 544 KB

english, 2005

22

Evaluation of a novel Vi conjugate vaccine in a murine model of salmonellosis

Christine Hale, Frances Bowe, Derek Pickard, Simon Clare, Jean-Francois Haeuw, Ultan Powers, Nathalie Menager, Pietro Mastroeni, Gordon Dougan

Journal:

Year:

2006

Language:

english

File:

PDF, 322 KB

english, 2006

23

Influence of live respiratory syncytial virus priming on the immune response generated by a recombinant vaccine candidate, BBG2Na

Liliane Goestch, Hélène Plotnicky-Gilquin, Thierry Champion, Alain Beck, Jean François Haeuw, Thien Nguyen, Jean Yves Bonnefoy, Nathalie Corvaı̈a

Journal:

Year:

2000

Language:

english

File:

PDF, 260 KB

english, 2000

24

BBG2Na an RSV subunit vaccine candidate intramuscularly injected to human confers protection against viral challenge after nasal immunization in mice

L Goetsch, H Plotnicky-Gilquin, J.P Aubry, P De-Lys, J.F Haeuw, J.Y Bonnefoy, N.T Nguyen, N Corvaı̈a, D Velin

Journal:

Year:

2001

Language:

english

File:

PDF, 140 KB

english, 2001

25

A novel bipolar mode of attachment to aluminium-containing adjuvants by BBG2Na, a recombinant subunit hRSV vaccine

Nathalie Dagouassat, Virginie Robillard, Jean-François Haeuw, Helène Plotnicky-Gilquin, Ultan F. Power, Nathalie Corvaı̈a, Thien Nguyen, Jean-Yves Bonnefoy, Alain Beck

Journal:

Year:

2001

Language:

english

File:

PDF, 290 KB

english, 2001

26

Streptococcus pneumoniae polysaccharides conjugated to the outer membrane protein A from Klebsiella pneumoniae elicit protective antibodies

Christine Libon, Jean François Haeuw, Françoise Crouzet, Chantal Mugnier, Jean Yves Bonnefoy, Alain Beck, Nathalie Corvaı̈a

Journal:

Year:

2002

Language:

english

File:

PDF, 196 KB

english, 2002

27

Outer membrane protein A (OmpA): a new pathogen-associated molecular pattern that interacts with antigen presenting cells—impact on vaccine strategies

Pascale Jeannin, Giovanni Magistrelli, Liliane Goetsch, Jean-Francois Haeuw, Nathalie Thieblemont, Jean-Yves Bonnefoy, Yves Delneste

Journal:

Year:

2002

Language:

english

File:

PDF, 72 KB

english, 2002

28

The outer membrane protein X from Escherichia coli exhibits immune properties

Karine Maisnier-Patin, Martine Malissard, Pascale Jeannin, Jean-François Haeuw, Jean-Claude Corbière, Guillaume Hoeffel, Jean-François Gauchat, Thien Nguyen, José M. Saez, Yves Delneste

Journal:

Year:

2003

Language:

english

File:

PDF, 288 KB

english, 2003

29

The serum albumin-binding region of streptococcal protein G (BB) potentiates the immunogenicity of the G130–230 RSV-A protein

Christine Libon, Nathalie Corvaı̈a, Jean-François Haeuw, Thien Ngoc Nguyen, Stefan Ståhl, Jean-Yves Bonnefoy, Christine Andreoni

Journal:

Year:

1999

Language:

english

File:

PDF, 943 KB

english, 1999

30

Chromosomal sequencing using a PCR-based biotin-capture method allowed isolation of the complete gene for the outer membrane protein A of Klebsiella pneumoniae

Thien Ngoc Nguyen, Patrik Samuelson, Fredrik Sterky, Christine Merle-Poitte, Alain Robert, Thierry Baussant, Jean-François Haeuw, Mathias Uhlén, Hans Binz, Stefan Ståhl

Journal:

Year:

1998

Language:

english

File:

PDF, 348 KB

english, 1998

31

P40: a promising new carrier protein

I. Rauly, L. Goestch, C. Libon, A. Beck, J.F. Haeuw, T.N. Guyen, T. Baussant, J.Y. Bonnefoy, N. Corvaia

Journal:

Research in Immunology

Year:

1998

Language:

english

File:

PDF, 88 KB

english, 1998

32

Involvement of LOX-1 in Dendritic Cell-Mediated Antigen Cross-Presentation

Yves Delneste, Giovanni Magistrelli, Jean-François Gauchat, Jean-François Haeuw, Jean-Pierre Aubry, Kayo Nakamura, Naoko Kawakami-Honda, Liliane Goetsch, Tatsuya Sawamura, Jean-Yves Bonnefoy, Pascale

Journal:

Year:

2002

Language:

english

File:

PDF, 387 KB

english, 2002

33

286 Generation of a recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) with an antitumor activity in a variety of human cancer xenograft models

I. Goetsch, A. Gonzalez, A. Beck, J.F. Haeuw, N. Corvaia

Journal:

European Journal of Cancer Supplements

Year:

2004

Language:

english

File:

PDF, 288 KB

english, 2004

34

A novel role for junctional adhesion molecule-A in tumor proliferation: Modulation by an anti-JAM-A monoclonal antibody

Goetsch, Liliane, Haeuw, Jean-François, Beau-Larvor, Charlotte, Gonzalez, Alexandra, Zanna, Laurence, Malissard, Martine, Lepecquet, Anne-Marie, Robert, Alain, Bailly, Christian, Broussas, Matthieu, C

Journal:

International Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 1.24 MB

english, 2013

35

522 POSTER Discovery of the 6F4 anti-tumor antibody targeting the tight junction molecule JAM-A. 1. Target identification by proteomic approach

J.F. Haeuw, L. Goetsch, L. Zanna, M. Malissard, V. Robillard, A.M. Lepecquet, A. Robert, C. Bailly, N. Corvaïa

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 92 KB

english, 2008

36

544 POSTER Discovery of the 6F4 anti-tumor antibody targeting the tight junction molecule JAM-A. 2. Target expression on human tumors and in vitro and in vivo anti-cancer activity

L. Goetsch, J.F. Haeuw, A. Gonzalez, C. Beau-Larvor, L. Zanna, T. Wurch, C. Bailly, N. Corvaïa

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 69 KB

english, 2008

37

225 515H7, a novel anti-chemokine receptor 4 (CXCR4) antibody. Part II: in vivo efficacy on CXCR4-dependent tumor models

C. Klinguer-Hamour, F. Geronimi, B. Akla, A. Robert, C. Tardy, A. Gerentet-de-Saluneaux, J.F. Haeuw, C. Bailly, L. Goetsch, N. Corvaia

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 47 KB

english, 2010

38

Scaled-Down Purification Protocol To Access Proteomic Analysis of 20S Proteasome from Human Tissue Samples: Comparison of Normal and Tumor Colorectal Cells

Ducoux-Petit, Manuelle, Uttenweiler-Joseph, Sandrine, Brichory, Franck, Bousquet-Dubouch, Marie-Pierre, Burlet-Schiltz, Odile, Haeuw, Jean-François, Monsarrat, Bernard

Journal:

Journal of Proteome Research

Year:

2008

Language:

english

File:

PDF, 3.91 MB

english, 2008

39

351 hz515H7, a humanized antibody exerts its antitumor activity via antagonism of the CXCR4/SDF-1 axis, and through effector functions

Klinguer-Hamour, C., Broussas, M., Akla, B., Berger, S., Boute, N., Beau-Larvor, C., Robert, A., Haeuw, J.F., Goetsch, L., Bailly, C., Corvaia, N.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 60 KB

english, 2014

40

Cancer Vaccine Design: A Novel Bacterial Adjuvant for Peptide-Specific CTL Induction

Miconnet, I., Coste, I., Beermann, F., Haeuw, J.-F., Cerottini, J.-C., Bonnefoy, J.-Y., Romero, P., Renno, T.

Journal:

The Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 253 KB

english, 2001

41

Protective Levels of Polysaccharide-Specific Maternal Antibodies May Enhance the Immune Response Elicited by Pneumococcal Conjugates in Neonatal and Infant Mice

Richter, M. Y., Jakobsen, H., Haeuw, J.-F., Power, U. F., Jonsdottir, I.

Journal:

Infection and Immunity

Year:

2005

Language:

english

File:

PDF, 194 KB

english, 2005

42

CD4+ T-Cell-Mediated Antiviral Protection of the Upper Respiratory Tract in BALB/c Mice following Parenteral Immunization with a Recombinant Respiratory Syncytial Virus G Protein Fragment

Plotnicky-Gilquin, H., Robert, A., Chevalet, L., Haeuw, J.-F., Beck, A., Bonnefoy, J.-Y., Brandt, C., Siegrist, C.-A., Nguyen, T. N., Power, U. F.

Journal:

Journal of Virology

Year:

2000

Language:

english

File:

PDF, 245 KB

english, 2000

43

Identification of B- and T-Cell Epitopes of BB, a Carrier Protein Derived from the G Protein of Streptococcus Strain G148

Goetsch, L., Haeuw, J. F., Champion, T., Lacheny, C., N'Guyen, T., Beck, A., Corvaia, N.

Journal:

Clinical and Vaccine Immunology

Year:

2003

Language:

english

File:

PDF, 1.33 MB

english, 2003

44

Challenge of BALB/c Mice with Respiratory Syncytial Virus Does Not Enhance the Th2 Pathway Induced after Immunization with a Recombinant G Fusion Protein, BBG2NA, in Aluminum Hydroxide

Corvaïa, Nathalie, Tournier, Patricia, Nguyen, Thien Ngoc, Haeuw, Jean François, Power, Ultan F., Binz, Hans, Andréoni, Christine

Journal:

The Journal of Infectious Diseases

Year:

1997

Language:

english

File:

PDF, 196 KB

english, 1997

45

Immunization of Female Mice with Glycoconjugates Protects Their Offspring against Encapsulated Bacteria

Richter, M. Y., Jakobsen, H., Birgisdottir, A., Haeuw, J.-F., Power, U. F., Del Giudice, G., Bartoloni, A., Jonsdottir, I.

Journal:

Infection and Immunity

Year:

2004

Language:

english

File:

PDF, 160 KB

english, 2004

46

Targeting of Nasal Mucosa-Associated Antigen-Presenting Cells In Vivo with an Outer Membrane Protein A Derived from Klebsiella pneumoniae

Goetsch, L., Gonzalez, A., Plotnicky-Gilquin, H., Haeuw, J. F., Aubry, J. P., Beck, A., Bonnefoy, J. Y., Corvaia, N.

Journal:

Infection and Immunity

Year:

2001

Language:

english

File:

PDF, 824 KB

english, 2001

47

Cytosolic glycosidases: do they exist?

Haeuw, Jean-Francois, Michalski, Jean-Claude, Strecker, Gerard, Spik, Genevieve, Montreuil, Jean

Journal:

Year:

1991

Language:

english

File:

PDF, 471 KB

english, 1991

48

Antibody-drug conjugate model fast characterization by LC-MS following IdeS proteolytic digestion

Wagner-Rousset, Elsa, Janin-Bussat, Marie-Claire, Colas, Olivier, Excoffier, Melissa, Ayoub, Daniel, Haeuw, Jean-François, Rilatt, Ian, Perez, Michel, Corvaïa, Nathalie, Beck, Alain

Journal:

Year:

2014

Language:

english

File:

PDF, 2.48 MB

english, 2014

49

A sensitive multidimensional method for the detection, characterization, and quantification of trace free drug species in antibody-drug conjugate samples using mass spectral detection

Birdsall, Robert E., McCarthy, Sean M., Janin-Bussat, Marie Claire, Perez, Michel, Haeuw, Jean-François, Chen, Weibin, Beck, Alain

Journal:

Year:

2015

Language:

english

File:

PDF, 2.01 MB

english, 2015

50

A new anti-CXCR4 antibody that blocks the CXCR4/SDF-1 axis and mobilizes effector cells

Broussas, M., Boute, N., Akla, B., Berger, S., Beau-Larvor, C., Champion, T., Robert, A., Beck, A., Haeuw, J.-F., Goetsch, L., Bailly, C., Dumontet, C., Matthes, T., Corvaia, N., Klinguer Hamour, C.

Journal:

Molecular Cancer Therapeutics

Year:

2016

Language:

english

File:

PDF, 868 KB

english, 2016

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